Diabetes
Researchers have shown that anthocyanins play an important role in diabetes and cardiovascular disease. Anthocyanins from aronia decreases the glucose levels in urine and decreases the TBARS (measure lipid oxidation) level in both urine and blood serum.
Other scientific groups have shown that anthocyanins from aronia decrease glycemic and HbAlc-glycosylated hemoglobin levels. Naruszewicz et al., (2000) conducted a cardiology clinical trial where patients with myocardial infarction (MI) were treated with aronia. This study suggested that aronia intake reduced systolic blood pressure in these patients. It was also illustrated that aronia reduced LDL oxidation and inhibited factors that mediated inflammation. Bell et al., at the Indiana School of Medicine (ISOM) showed that of all berry extracts tested, aronia provided complete cellular protection from oxidative injury and had a direct vasorelaxation effect on the arterial endothelium through the stimulation of nitric oixide (NO).
A further study through ISOM and a cardiology practice showed increased flow mediated dilation of the brachial artery in human subjects.
A 2002 animal-modeled study (Kowalczyk et al), conducted in the Department of Pharmacology of the Military MedicalAcademy, Lodz, Poland, tested anthocyanins from the aronia berry.
The study concluded that aronia berry anthocyanins might be useful in combating “oxidative stress” in cardiovascular patients. Yet another study (Simeonov et al, 2002) conducted at the Medical University in Plovdiv, Bulgaria, found that chokeberry juice without sugar added (artificially sweetened) was “a valuable adjunct” to treating patients with diabetes. Another Bulgarian study (Borissova et al, 1994) showed that chokeberry juice, due to its anthocyanine flavonoids, had an anti-inflammatory value, when inflammation was induced by histamine & serotonin. Additional studies have been conducted, either proving or hinting at possibilities of staggering health benefits for blood circulation, urinary tracthealth, heart health and gastrointestinal health.
Hypoglycemic and hypolipidemic effects of Aronia melanocarpa fruit juice in streptozotocin-induced diabetic rats.
Methods Find Exp Clin Pharmacol. 2007 Mar;29(2):101-5. Valcheva-Kuzmanova S, Kuzmanov K, Tancheva S, Belcheva A. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University, Varna, Bulgaria.
Aronia melanocarpa fruit juice is rich in phenolic antioxidants, especially flavonoids from the anthocyanin subclass. The aim of the present study was to investigate the influence of Aronia melanocarpa fruit juice on plasma glucose and lipids in diabetic rats. Aronia melanocarpa fruit juice significantly decreased the streptozotocin-induced abnormalities in blood glucose and triblycerides in diabetic rats and might be useful in prevention and control of diabetes mellitus and diabetes-associated complications.
Diabetes Studies:
Researchers have shown that anthocyanins play an important role in diabetes and cardiovascular disease. Anthocyanins from aronia decreases the glucose levels in urine and decreases the TBARS (measure lipid oxidation) level in both urine and blood serum.
Other scientific groups have shown that anthocyanins from aronia decrease glycemic and HbAlc-glycosylated hemoglobin levels. Naruszewicz et al., (2000) conducted a cardiology clinical trial where patients with myocardial infarction (MI) were treated with aronia. This study suggested that aronia intake reduced systolic blood pressure in these patients. It was also illustrated that aronia reduced LDL oxidation and inhibited factors that mediated inflammation. Bell et al., at the Indiana School of Medicine (ISOM) showed that of all berry extracts tested, aronia provided complete cellular protection from oxidative injury and had a direct vasorelaxation effect on the arterial endothelium through the stimulation of nitric oixide (NO).
A further study through ISOM and a cardiology practice showed increased flow mediated dilation of the brachial artery in human subjects.
A 2002 animal-modeled study (Kowalczyk et al), conducted in the Department of Pharmacology of the Military MedicalAcademy, Lodz, Poland, tested anthocyanins from the aronia berry. The study concluded that aronia berry anthocyanins might be useful in combating “oxidative stress” in cardiovascular patients. Yet another study (Simeonov et al, 2002) conducted at the Medical University in Plovdiv, Bulgaria, found that chokeberry juice without sugar added (artificially sweetened) was “a valuable adjunct” to treating patients withdiabetes. Another Bulgarian study (Borissova et al, 1994) showed that chokeberry juice, due to its anthocyane flavonoids, had an anti-inflammatory value, when inflammation was induced by histamine & serotonin. Additional studies have been conducted, either proving or hinting at possibilities of staggering health benefits for blood circulation, urinary tracthealth, heart health and gastrointestinal health.
Hypoglycemic and hypolipidemic effects of Aronia melanocarpa fruit juice in streptozotocin-induced diabetic rats.
Methods Find Exp Clin Pharmacol. 2007 Mar;29(2):101-5. Valcheva-Kuzmanova S, Kuzmanov K, Tancheva S, Belcheva A. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University, Varna, Bulgaria.
Aronia melanocarpa fruit juice is rich in phenolic antioxidants, especially flavonoids from the anthocyanin subclass. The aim of the present study was to investigate the influence of Aronia melanocarpa fruit juice on plasma glucose and lipids in diabetic rats. Aronia melanocarpa fruit juice significantly decreased the streptozotocin-induced abnormalities in blood glucose and triblycerides in diabetic rats and might be useful in prevention and control of diabetes mellitus and diabetes-associated complications.
